Animal Studies
The safety of MZ has been evaluated in a recent toxicity trial using a small animal model. The results of this trial verified that the 'No-Observed-Adverse-Effect-Level' (NOAEL) was in excess of 200 mg/kg/day, far greater than doses used in dietary supplements which are typically less than 0.5 mg/kg/day.
Absence of mutagenicity was confirmed by the Ames test. MZ is also a regular dietary component in countries where it is a major pigment used by the poultry industry, particularly Mexico, and no adverse effects have been reported.
MZ is also a regular dietary component in countries where it is a major pigment used by the poultry industry.
The NOAEL effect of MZ is far greater than doses used in dietary supplements.